Genes are biochemical recipes written in a four-letter alphabet called DNA.

Progress and success are always relative. When the land was unoccupied by animals, the first amphibian to emerge from the sea could get away with being slow, lumbering, and fish-like, for it had no enemies and no competitors. But if a fish were to take to the land today, it would be gobbled up by a passing fox as surely as a Mongol horde would be wiped out by machine guns. In history and in evolution, progress is always a futile, Sisyphean struggle to stay in the same relative place by getting ever better at things.

TP53 seems to encode the greater good, like a suicide pill in the mouth of a soldier that dissolves only when it detects evidence that he is about to mutiny.