Science is human behavior, and so is the opposition to science.

Theories — whether neural, mental, or conceptual — talk about intervening steps in these relationships. But instead of prompting us to search for and explore relevant variables, they frequently have quite the opposite effect. When we attribute behavior to a neural or mental event, real or conceptual, we are likely to forget that we still have the task of accounting for the neural or mental event. ...Research designed with respect to theory is also likely to be wasteful. That a theory generates research does not prove its value unless the research is valuable. Much useless experimentation results from theories, and much energy and skill is absorbed by them. Most theories are eventually overthrown, and the greater part of the associated research is discarded.

A failure is not always a mistake. It may simply be the best one can do under the circumstances. The real mistake is to stop trying.